Author: The Guardian

Red light, red light?For much of Sir Alex Ferguson’s time in charge of Manchester United, a nugget of wisdom was repeated over and over again across the footballing world. No, not “you’re all bloody idiots”, but “when you leave Old Trafford the only way out is failure”. Gerard Pique was the first to unintentionally challenge this, taking the unlikely shortcut from Manchester United’s reserves to perhaps the greatest club side of all time. However, when Ferguson retired in 2013, this cliché was turned on its head. When you enter Old Trafford in 2024, the only way out is down –…

Scientists have discovered an entirely new class of antibiotic that appears to kill one of three bacteria considered to pose the greatest threat to human health because of their extensive drug-resistance.Zosurabalpin defeated highly drug-resistant strains of Carbapenem-resistant Acinetobacter baumannii (Crab) in mouse models of pneumonia and sepsis, and was being tested in human trials.Crab is classified as a priority 1 critical pathogen by the World Health Organization, alongside two other drug-resistant forms of bacteria – Pseudomonas aeruginosa and Enterobacteriaceae.“Crab is a significant cause of infection in hospitals, particularly in people who are on ventilators,” said Dr Andrew Edwards, a senior…

timeThe rise of 16-year-old Luke Littler at the PDC Darts World Championship in London will become one of the sporting stories of the year. He may have become the favorite to win the BBC Sports Personality of the Year award in December. As a teenage sports star, he surrounded himself with distinguished people.skinIn 1958, Edson Arantes do Nascimento, better known as Pelé, scored in every knockout match to help Brazil win in Sweden Won the first Men’s World Cup. The then 17-year-old Pele went on to become a standout player of his era and a cornerstone of the Brazilian team.…

Two explosions have killed at least 103 people and injured scores more at a memorial ceremony in Iran marking the fourth anniversary of the US killing of Qassem Suleimani, the head of Iran’s Quds Force and one of the most powerful men in the Middle East.A senior official called the blasts a “terroristic” attack, without elaborating on who could be behind them. No one has immediately claimed responsibility for what appeared to be the deadliest attack to target Iran since its 1979 Islamic Revolution.Eyewitness reports spoke of two explosions 10 minutes apart in the south-central city of Kerman, while some…

It looked easy, and it was, as the world’s newest sports star later admitted. “I don’t think I’ve had any difficulties,” Luke Littler said after beating Rob Cross 6-2 to reach his first world championship final.”I don’t think anything has been difficult for me, and I don’t mean to be disrespectful to anyone I’ve met. It’s 3-2 in a few sets. But I just believe in myself and my abilities.” No matter today What happened in the late final against new world number one Luke Humphreys, Littler’s life and the game of darts had changed forever.Reaching the world finals in…

The US government cannot enforce federal guidance in Texas requiring emergency room doctors to perform abortions if necessary to stabilize emergency room patients, a federal appeals court ruled on Tuesday, siding with the state in a lawsuit accusing Joe Biden’s administration of overstepping its authority.The ruling by a unanimous panel of the fifth US circuit court of appeals comes amid a wave of lawsuits focusing on when abortions can be provided in states whose abortion bans have exceptions for medical emergencies.The US department of justice declined to comment. The office of Ken Paxton, the Texas attorney general and two anti-abortion…

As the rain continued to fall over Anfield and a frantic game between Liverpool and Newcastle unfolded, Eddie Howe stared down January as the cruelest month yet for his employment prospects.Jurgen Klopp’s side could have beaten their opponents 8-2 but ended up beating their opponents 4-2. This was horrific for Howe as it left Newcastle with just one win in eight games. In other words: Saudi Arabia’s Public Investment Fund football project has lost seven of its last eight games, and their next three games scheduled until February look like this time at Anfield The journey is just as dangerous.On…

Key eventsShow key events onlyPlease turn on JavaScript to use this feature62 min Lovely feet from Diaz, who makes room for a shot from the edge of the area that is beaten away by Dubravka as he falls to his right. A Liverpool goal feels inevitable.Updated at 22.24 CET60 min Alexander-Arnold’s dangerous ball is missed by the stretching Diaz and kicked nervously across his own six-yard box by Livramento. He gets away with it. Moments later Diaz, who has been his 2021-22 self tonight, Cruyff-turns Livramento and pokes the ball right across the face.60 min The xG according to Flashscore is…

A Kentucky woman unexpectedly learned she would lose her legs and arms in what she thought was a relatively routine episode of kidney stones, but she’s facing her predicament by focusing on what she still has.”I’m just happy to be alive,” Lucinda “Cindy” Mullins, who raises two sons with her husband, recently told Kentucky news station WLEX. “I can see my kids. I can see my family. I can spend time with my husband.”I’m just saying these are the cards I’ve been dealt and these are the cards I’m going to play. … These are small things right now.”As she…

A Labour government should make the UK the world’s first country to make policy based on its impact on wellbeing as well as the economy, one of the world’s leading experts on the economics of happiness has said.With Keir Starmer in No 10, Downing Street should require Whitehall departments to appraise the potential impact on citizens’ wellbeing when they make funding bids, Richard Layard said. The next chancellor should announce measures of happiness and misery alongside GDP in their annual budget statements, he added.The call comes as it emerged a research agency set up under David Cameron to help to…